Drug Combination Details
| General Information of the Combination (ID: C64244) | |||||
|---|---|---|---|---|---|
| Name | Schisandrol B NP Info | + | Cisplatin Drug Info | ||
| Structure |
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| Disease |
Healthy individual
[ICD-11: N.A.]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | The experiments were carried out on male Balb/c mice (8 - 10 weeks old). | |||||
| Experimental
Result(s) |
Schisandrin B, attenuates cisplatin-induced oxidative stress, genotoxicity and neurotoxicity through modulating NF-KappaB pathway in mice. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Schisandrin B, attenuates cisplatin-induced oxidative stress, genotoxicity and neurotoxicity through modulating NF-KappaB pathway in mice. Free Radic Res. 2012 Jan;46(1):50-60. | |||
