Drug Combination Details

General Information of the Combination (ID: C68358)
Name Glucosamine   NP Info  + Tacrolimus   Drug Info 
Structure +
Disease
Skin lesions [ICD-11: ME60]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vivo Model NC/Nga mice Induction of AD using Df body ointment was performed.
                    Experimental
                    Result(s)		 Combination therapy of glucosamine plus FK-506 was more synergistic efficacy than single-modality treatment with either alone to improve the development of established dermatitis in NC/Nga mice model.
References
Reference 1 Therapeutic effects of combination using glucosamine plus tacrolimus (FK-506) on the development of atopic dermatitis-like skin lesions in NC/Nga mice. Scand J Immunol. 2012 May;75(5):471-8.
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