Drug Combination Details
| General Information of the Combination (ID: C70279) | |||||
|---|---|---|---|---|---|
| Name | Magnesium NP Info | + | Ketamine Drug Info | ||
| Structure |
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+ |
|
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| Disease |
Pain
[ICD-11: MG30-MG3Z]
|
Phase 4 | [1] | ||
|
Hyperthermia
[ICD-11: MG26]
|
Investigative | [2] | |||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [2] | |||||
| In-vivo Model | A total of one hundred and seventy-four Wistar rats (200-250 g) were used in the entire study. | |||||
| Experimental
Result(s) |
Fixed low dose of magnesium sulfate enhanced the temperature lowering effect of ketamine on baseline body temperature and morphine-induced hyperthermia. | |||||
