Drug Combination Details
| General Information of the Combination (ID: C73606) | |||||
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| Name | Vinblastine | + | Methotrexate + Radiation | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Vinblastine NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
| Structure |
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| Disease |
Fibromatosis
[ICD-11: FB51]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Experimental
Result(s) |
Low-dose chemotherapy with methotrexate and vinblastine for 1 year was effective and well tolerated by adult patients with aggressive, recurrent fibromatosis. | |||||
| References | ||||
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| Reference 1 | Combination chemotherapy with methotrexate and vinblastine for surgically unresectable, aggressive fibromatosis. Jpn J Clin Oncol. 2016 Sep;46(9):845-9. | |||