Drug Combination Details
| General Information of the Combination (ID: C75169) | |||||
|---|---|---|---|---|---|
| Name | Artemisinin NP Info | + | Sodium butyrate Drug Info | ||
| Structure |
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+ |
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| Disease |
Acute lymphoblastic leukemia
[ICD-11: 2B33]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Biological
Regulation |
Up-regulation | Apoptosis | ||||
| In-vitro Model | MOLT-4 | CVCL_0013 | Adult T acute lymphoblastic leukemia | Homo sapiens | ||
| Experimental
Result(s) |
DHA in combination with butyric acid acts synergistically at low doses. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. Anticancer Res. Nov-Dec 2005;25(6B):4325-31. | |||
