Drug Combination Details

General Information of the Combination (ID: C83293)
Name Vitamin C   NP Info  + Cisplatin   Drug Info 
Structure +
Disease
Stomach cancer [ICD-11: 2B72]
Investigative [1]
Anaplastic large cell lymphoma [ICD-11: 2A90]
Investigative [2]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [2]
                    Experimental
                    Result(s)		 Ascorbic acid renders cisplatin more effective as an antitumor agent.
References
Reference 1 Synergistic Effect of Vitamin C with Cisplatin for Inhibiting Proliferation of Gastric Cancer Cells. Iran Biomed J. 2020 Mar;24(2):119-27.
Reference 2 Chemo-immunotherapeutical studies on Dalton's lymphoma in mice using cisplatin and ascorbic acid: synergistic antitumor effect in vivo and in vitro. Arch Immunol Ther Exp (Warsz). 1993;41(5-6):327-33.
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