Drug Combination Details
| General Information of the Combination (ID: C85456) | |||||
|---|---|---|---|---|---|
| Name | Cryptoxanthin NP Info | + | Cisplatin Drug Info | ||
| Structure |
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+ |
|
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| Disease |
Stomach cancer
[ICD-11: 2B72]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | BCL-2 | Molecule Info |
Pathway MAP
|
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| In-vitro Model | BGC-823 | CVCL_3360 | Gastric cancer | Homo sapiens | ||
| Experimental
Result(s) |
The combination of crocin with cisplatin suppresses growth of gastric carcinoma cell line BGC-823 and promotes cell apoptosis. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | The combination of crocin with cisplatin suppresses growth of gastric carcinoma cell line BGC-823 and promotes cell apoptosis. Pak J Pharm Sci. 2017 Sep;30(5):1629-1634. | |||
