Drug Combination Details
| General Information of the Combination (ID: C88236) | |||||
|---|---|---|---|---|---|
| Name | Omega-3 PUFAs NP Info | + | Naproxen Drug Info | ||
| Structure |
|
+ |
|
||
| Disease |
Obesity
[ICD-11: 5B81]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | VCAM1 | Molecule Info |
Pathway MAP
|
|
| Biological
Regulation |
Decrease | Serum TG | ||||
| In-vivo Model | Clinical trial | |||||
| Experimental
Result(s) |
Combining NX with omega-3 PUFAs increases their effectiveness in reducing serum TG and favorably altering AT gene expression and plasma bile acid profile. | |||||
