| General Information of the NP (ID: NP0843) |
| Name |
Cedrol
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| Species Origin |
Juniperus virginiana ...
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| Juniperus virginiana |
SuperKingdom: Eukaryota
Kingdom: Viridiplantae
Phylum: Tracheophyta
Class: Pinopsida
Order: Cupressales
Family: Cupressaceae
Genus: Juniperus
Species: Juniperus virginiana
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| Disease |
Androgenetic alopecia
[ICD-11: ED70] |
Investigative |
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| Structure |
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Click to Download Mol
2D MOL
3D MOL
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| ADMET Property |
Absporption
Caco-2 Permeability
-4.742
MDCK Permeability
-4.538
Distribution
Metabolism
CYP1A2 inhibitor
- - -
CYP1A2 substrate
- - -
CYP2C19 inhibitor
- -
CYP2C19 substrate
+++
CYP2C9 inhibitor
-
CYP2C9 substrate
- - -
CYP2D6 inhibitor
- -
CYP2D6 substrate
- - -
CYP3A4 inhibitor
- - -
CYP3A4 substrate
+++
CYP2B6 inhibitor
+++
CYP2B6 substrate
- - -
CYP2C8 inhibitor
+++
HLM Stability
- - -
Excretion
CLplasma
16.679
T1/2
1.384
Toxicity
DILI
- -
Rat Oral Acute Toxicity
-
Human Hepatotoxicity
+
Ototoxicity
-
Drug-induced Nephrotoxicity
+
Drug-induced Neurotoxicity
- -
Hematotoxicity
-
Genotoxicity
- -
Tips: 1. For the classification endpoints, the prediction probability values are transformed into six symbols: 0-0.1 (- - -), 0.1-0.3 (- -), 0.3-0.5 (-), 0.5-0.7 (+), 0.7-0.9 (++), and 0.9-1.0 (+++).
2. Additionally, the corresponding relationships of the three labels are as follows: excellent; medium; poor.
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Click to Show/Hide the Molecular Information and External Link(s) of This Natural Product
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| Formula |
C15H26O
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| PubChem CID |
|
| Canonical SMILES |
C[C@@H]1CC[C@@H]2[C@]13CC[C@@]([C@H](C3)C2(C)C)(C)O
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| InChI |
InChI=1S/C15H26O/c1-10-5-6-11-13(2,3)12-9-15(10,11)8-7-14(12,4)16/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m1/s1
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| InChIKey |
SVURIXNDRWRAFU-OGMFBOKVSA-N
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| CAS Number |
77-53-2
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| ChEBI ID |
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