Natural Product (NP) Details

General Information of the NP (ID: NP5727)
Name
L-methionine
Synonyms
L-methionine; 63-68-3; methionine; h-Met-oh; (S)-2-Amino-4-(methylthio)butanoic acid; Cymethion; L-(-)-Methionine; Liquimeth; S-Methionine; L-Methioninum; Methilanin; Neo-methidin; (L)-Methionine; Methionine (VAN); Acimethin; Metionina [DCIT]; (S)-methionine; L-alpha-Amino-gamma-methylmercaptobutyric acid; h-Met-h; Methioninum [INN-Latin]; metionina; Methioninum; Polymethionine; L-Homocysteine, S-methyl-; L-Methionin; (2S)-2-amino-4-(methylsulfanyl)butanoic acid; METHIONINE, L-; Poly-L-methionine; L(-)-Amino-gamma-methylthiobutyric acid; L-alpha-Amino-gamma-methylthiobutyric acid; L-gamma-Methylthio-alpha-aminobutyric acid; met; CCRIS 5528; CCRIS 5536; HSDB 4317; 2-Amino-4-methylthiobutanoic acid (S)-; UNII-AE28F7PNPL; (S)-2-amino-4-(methylthio)butyric acid; 2-Amino-4-(methylthio)butyric acid, (S)-; (2S)-2-amino-4-methylsulfanyl-butanoic acid; MFCD00063097; L-Met; Butanoic acid, 2-amino-4-(methylthio)-, (S)-; Toxin WAR (Bacillus thuringiensis strain PS205C); L-a-Amino-g-methylthiobutyric acid; S-Methyl-L-homocysteine; (S)-(+)-Methionine; AE28F7PNPL; gamma-Methylthio-alpha-aminobutyric acid; L-2-Amino-4-(methylthio)butanoic acid; CHEMBL42336; (2S)-2-Amino-4-methylsulfanylbutanoic acid; CHEBI:16643; L-2-Amino-4methylthiobutyric acid; L-Methionine-35S; L-Methionine, 98+%; (S)-2-Amino-4-(methylmercapto)butyric acid; 58576-49-1; Methionine [USAN:INN]; C-11 Methionine; l-2-Amino-4-(methylthio)butyric acid; EINECS 200-562-9; (2S)-2-amino-4-(methylsulfanyl)butanoate; NSC 22946; C-11 Met; NSC-22946; 3h-l-methionine; g-Methylthio-a-aminobutyric acid; racemic methionine; 1wkm; Methionine [USAN:USP:INN:BAN]; Toxin WAR; (35S)Methionine; 2-Amino-4-(methylthio)butyrate; Methionine (USP); a-Amino-g-methylmercaptobutyric acid; L-Methionine,(S); NSC 118113; 3654-96-4; L-S-methylhomocysteine; PubChem14349; 1pg2; 1qq9; L-Methionine Z (TN); L-Methionine (JP17); L-Methionine, homopolymer; Methionine, L- (8CI); bmse000044; bmse000915; SCHEMBL4226; G-methylthio-a-aminobutyrate; L-Methionine (H-Met-OH); H-Met-2-Chlorotrityl Resin; 2-Amino-4-methylthiobutanoate; L-a-amino-g-methylthiobutyrate; GTPL4814; A-amino-g-methylmercaptobutyrate; DTXSID5040548; SCHEMBL15702352; Pharmakon1600-01301006; alpha-amino-alpha-aminobutyric acid; gamma-methylthio-alpha-aminobutyrate; HY-N0326; L-Methionine, Cell Culture Reagent; ZINC1532529; L-2-Amino-4-methylthiobutyric acid; ANW-34703; BDBM50142500; MFCD00801344; NSC760117; s5633; L-alpha-amino-gamma-methylthiobutyrate; L-Methionine, Vetec(TM), 98.5%; (S)-2-Amino-4-(methylthio)butanoate; AKOS000281626; AKOS015852512; L-Methionine, labeled with carbon-11; alpha-amino-gamma-methylmercaptobutyrate; CCG-266196; CS-W020566; DB00134; MCULE-7228063662; NSC-760117; (S)-2-amino-4-(methylthio)-Butanoate; NCGC00160620-01; NCGC00160620-02; AS-10898; (S)-2-amino-4-(methylthio)-Butanoic acid; AB0008395; DB-029971; L-Methionine, BioUltra, >=99.5% (NT); 988-EP0930075A1; 988-EP1441224A2; 988-EP2269610A2; 988-EP2269977A2; 988-EP2269978A2; 988-EP2269979A1; 988-EP2269985A2; 988-EP2269989A1; 988-EP2269990A1; 988-EP2269991A2; 988-EP2269992A1; 988-EP2269993A1; 988-EP2269996A1; 988-EP2270001A1; 988-EP2270003A1; 988-EP2270005A1; 988-EP2270006A1; 988-EP2270008A1; 988-EP2270010A1; 988-EP2270011A1; 988-EP2270014A1; 988-EP2270017A1; 988-EP2270018A1; 988-EP2270114A1; 988-EP2270895A2; 988-EP2272509A1; 988-EP2272516A2; 988-EP2272517A1; 988-EP2272817A1; 988-EP2272825A2; 988-EP2272826A1; 988-EP2272827A1; 988-EP2272828A1; 988-EP2272834A1; 988-EP2272838A1; 988-EP2272841A1; 988-EP2272842A1; 988-EP2272844A1; 988-EP2272845A2; 988-EP2272846A1; 988-EP2272972A1; 988-EP2272973A1; 988-EP2275102A1; 988-EP2275105A1; 988-EP2275401A1; 988-EP2275403A1; 988-EP2275404A1; 988-EP2275412A1; 988-EP2275413A1; 988-EP2275414A1; 988-EP2275420A1; 988-EP2275421A1; 988-EP2275469A1; 988-EP2277565A2; 988-EP2277566A2; 988-EP2277567A1; 988-EP2277568A2; 988-EP2277569A2; 988-EP2277570A2; 988-EP2277848A1; 988-EP2277867A2; 988-EP2277868A1; 988-EP2277869A1; 988-EP2277872A1; 988-EP2277874A1; 988-EP2277875A2; 988-EP2277876A1; 988-EP2277877A1; 988-EP2277880A1; 988-EP2277881A1; 988-EP2277882A1; 988-EP2277898A2; 988-EP2278637A1; 988-EP2279741A2; 988-EP2279750A1; 988-EP2280003A2; 988-EP2280006A1; 988-EP2280008A2; 988-EP2280009A1; 988-EP2280010A2; 988-EP2280012A2; 988-EP2280014A2; 988-EP2280282A1; 988-EP2281559A1; 988-EP2281563A1; 988-EP2281812A1; 988-EP2281815A1; 988-EP2281819A1; 988-EP2281820A2; 988-EP2281822A1; 988-EP2281824A1; 988-EP2283898A1; 988-EP2284149A1; 988-EP2284150A2; 988-EP2284151A2; 988-EP2284152A2; 988-EP2284153A2; 988-EP2284154A1; 988-EP2284155A2; 988-EP2284156A2; 988-EP2284157A1; 988-EP2284158A1; 988-EP2284159A1; 988-EP2284160A1; 988-EP2284164A2; 988-EP2284165A1; 988-EP2284169A1; 988-EP2284171A1; 988-EP2284172A1; 988-EP2284174A1; 988-EP2284178A2; 988-EP2284179A2; 988-EP2284920A1; 988-EP2286811A1; 988-EP2286812A1; 988-EP2286915A2; 988-EP2287140A2; 988-EP2287141A1; 988-EP2287147A2; 988-EP2287148A2; 988-EP2287150A2; 988-EP2287156A1; 988-EP2287159A1; 988-EP2287161A1; 988-EP2287162A1; 988-EP2287163A1; 988-EP2287165A2; 988-EP2287166A2; 988-EP2287167A1; 988-EP2287168A2; 988-EP2287940A1; 988-EP2289510A1; 988-EP2289868A1; 988-EP2289871A1; 988-EP2289876A1; 988-EP2289880A1; 988-EP2289881A1; 988-EP2289882A1; 988-EP2289883A1; 988-EP2289886A1; 988-EP2289887A2; 988-EP2289888A2; 988-EP2289890A1; 988-EP2289891A2; 988-EP2289892A1; 988-EP2289893A1; 988-EP2289894A2; 988-EP2292088A1; 988-EP2292227A2; 988-EP2292228A1; 988-EP2292280A1; 988-EP2292576A2; 988-EP2292589A1; 988-EP2292590A2; 988-EP2292593A2; 988-EP2292597A1; 988-EP2292608A1; 988-EP2292610A1; 988-EP2292614A1; 988-EP2292615A1; 988-EP2292617A1; 988-EP2292620A2; 988-EP2292621A1; 988-EP2292622A1; 988-EP2292625A1; 988-EP2292628A2; 988-EP2292630A1; 988-EP2295399A2; 988-EP2295401A2; 988-EP2295406A1; 988-EP2295407A1; 988-EP2295408A1; 988-EP2295410A1; 988-EP2295411A1; 988-EP2295412A1; 988-EP2295413A1; 988-EP2295415A1; 988-EP2295416A2; 988-EP2295417A1; 988-EP2295418A1; 988-EP2295419A2; 988-EP2295422A2; 988-EP2295423A1; 988-EP2295426A1; 988-EP2295427A1; 988-EP2295428A2; 988-EP2295429A1; 988-EP2295432A1; 988-EP2295433A2; 988-EP2295434A2; 988-EP2295436A1; 988-EP2295437A1; 988-EP2295438A1; 988-EP2295439A1; 988-EP2295441A2; 988-EP2295550A2; 988-EP2298077A1; 988-EP2298305A1; 988-EP2298728A1; 988-EP2298732A1; 988-EP2298734A2; 988-EP2298735A1; 988-EP2298736A1; 988-EP2298738A1; 988-EP2298742A1; 988-EP2298743A1; 988-EP2298744A2; 988-EP2298746A1; 988-EP2298747A1; 988-EP2298748A2; 988-EP2298749A1; 988-EP2298752A1; 988-EP2298754A1; 988-EP2298755A1; 988-EP2298758A1; 988-EP2298759A1; 988-EP2298761A1; 988-EP2298762A2; 988-EP2298763A1; 988-EP2298766A1; 988-EP2298767A1; 988-EP2298768A1; 988-EP2298769A1; 988-EP2298770A1; 988-EP2298773A1; 988-EP2298775A1; 988-EP2298776A1; 988-EP2298778A1; 988-EP2298779A1; 988-EP2298780A1; 988-EP2298783A1; 988-EP2298828A1; 988-EP2299785A1; 988-EP2301533A1; 988-EP2301534A1; 988-EP2301536A1; 988-EP2301538A1; 988-EP2301544A1; 988-EP2301911A1; 988-EP2301913A1; 988-EP2301914A1; 988-EP2301922A1; 988-EP2301923A1; 988-EP2301928A1; 988-EP2301929A1; 988-EP2301931A1; 988-EP2301932A1; 988-EP2301933A1; 988-EP2301935A1; 988-EP2301936A1; 988-EP2301937A1; 988-EP2301939A1; 988-EP2301940A1; 988-EP2301983A1; 988-EP2302132A1; 988-EP2305033A1; 988-EP2305250A1; 988-EP2305260A1; 988-EP2305629A1; 988-EP2305636A1; 988-EP2305637A2; 988-EP2305640A2; 988-EP2305641A1; 988-EP2305642A2; 988-EP2305643A1; 988-EP2305644A1; 988-EP2305648A1; 988-EP2305651A1; 988-EP2305652A2; 988-EP2305660A1; 988-EP2305664A1; 988-EP2305668A1; 988-EP2305669A1; 988-EP2305671A1; 988-EP2305672A1; 988-EP2305674A1; 988-EP2305675A1; 988-EP2305676A1; 988-EP2305678A1; 988-EP2305680A2; 988-EP2305682A1; 988-EP2305684A1; 988-EP2305688A1; 988-EP2305689A1; 988-EP2305695A2; 988-EP2305696A2; 988-EP2305697A2; 988-EP2305698A2; 988-EP2305769A2; 988-EP2305808A1; 988-EP2306788A1; 988-EP2306789A1; 988-EP2308479A2; 988-EP2308562A2; 988-EP2308812A2; 988-EP2308828A2; 988-EP2308832A1; 988-EP2308838A1; 988-EP2308839A1; 988-EP2308840A1; 988-EP2308841A2; 988-EP2308844A2; 988-EP2308845A2; 988-EP2308846A2; 988-EP2308849A1; 988-EP2308850A1; 988-EP2308851A1; 988-EP2308852A1; 988-EP2308854A1; 988-EP2308855A1; 988-EP2308858A1; 988-EP2308861A1; 988-EP2308863A1; 988-EP2308866A1; 988-EP2308867A2; 988-EP2308868A1; 988-EP2308869A1; 988-EP2308870A2; 988-EP2308872A1; 988-EP2308873A1; 988-EP2308874A1; 988-EP2308875A1; 988-EP2308876A1; 988-EP2308877A1; 988-EP2308878A2; 988-EP2308879A1; 988-EP2308880A1; 988-EP2308882A1; 988-EP2308960A1; 988-EP2311451A1; 988-EP2311455A1; 988-EP2311494A1; 988-EP2311796A1; 988-EP2311797A1; 988-EP2311798A1; 988-EP2311799A1; 988-EP2311801A1; 988-EP2311802A1; 988-EP2311803A1; 988-EP2311806A2; 988-EP2311807A1; 988-EP2311808A1; 988-EP2311809A1; 988-EP2311810A1; 988-EP2311811A1; 988-EP2311814A1; 988-EP2311816A1; 988-EP2311817A1; 988-EP2311822A1; 988-EP2311825A1; 988-EP2311826A2; 988-EP2311827A1; 988-EP2311828A1; 988-EP2311829A1; 988-EP2311830A1; 988-EP2311831A1; 988-EP2311836A1; 988-EP2311837A1; 988-EP2311842A2; 988-EP2311850A1; 988-EP2314295A1; 988-EP2314574A1; 988-EP2314576A1; 988-EP2314579A1; 988-EP2314580A1; 988-EP2314581A1; 988-EP2314582A1; 988-EP2314583A1; 988-EP2314587A1; 988-EP2314588A1; 988-EP2314590A1; 988-EP2314591A1; 988-EP2314593A1; 988-EP2315303A1; 988-EP2315502A1; 988-EP2316450A1; 988-EP2316452A1; 988-EP2316457A1; 988-EP2316458A1; 988-EP2316824A1; 988-EP2316825A1; 988-EP2316826A1; 988-EP2316827A1; 988-EP2316828A1; 988-EP2316829A1; 988-EP2316830A2; 988-EP2316831A1; 988-EP2316832A1; 988-EP2316833A1; 988-EP2316836A1; 988-EP2316905A1; 988-EP2316906A2; 988-EP2316937A1; 988-EP2371806A1; 988-EP2371807A1; 988-EP2371808A1; 988-EP2371813A1; 988-EP2371814A1; 988-EP2371823A1; 988-EP2374454A1; 988-EP2374533A1; 988-EP2374787A1; 988-EP2374790A1; 988-EP2374791A1; 988-EP2375479A1; 988-EP2377845A1; 988-EP2377849A2; 988-EP2380871A1; 988-EP2380873A1; A5456; AM20100552; M0099; L-Methionine, SAJ special grade, >=98.5%; 63M683; C00073; D00019; L(-)-amino-alpha-amino-alpha-aminobutyric acid; L-Methionine, reagent grade, >=98% (HPLC); M-6051; M02939; M02945; 88843-EP2289892A1; 88843-EP2305825A1; L-Methionine, Vetec(TM) reagent grade, >=98%; C6CB5837-2B49-4B25-AAB0-D305DAFE26EB; Q22124685; F1905-8241; Z1250208671; L-Methionine, certified reference material, TraceCERT(R); Methionine, European Pharmacopoeia (EP) Reference Standard; UNII-0O72R8RF8A component FFEARJCKVFRZRR-BYPYZUCNSA-N; UNII-73JWT2K6T3 component FFEARJCKVFRZRR-BYPYZUCNSA-N; UNII-N7U7BXP2OI component FFEARJCKVFRZRR-BYPYZUCNSA-N; N-(2CT Resin)-L-Met-OH (200-400 mesh, > 0.3 mmol/g); L-Methionine,
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Species Origin Chenopodium quinoa ...     Click to Show/Hide
Chenopodium quinoa
Kingdom: Viridiplantae
Phylum: Streptophyta
Class: Magnoliopsida
Order: Caryophyllales
Family: Chenopodiaceae
Genus: Chenopodium
Species: Chenopodium quinoa
Disease Pancreatic cancer [ICD-11: 2C10] Investigative [1]
Structure
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2D MOL

3D MOL

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Formula
C5H11NO2S
PubChem CID
6137
Canonical SMILES
CSCCC(C(=O)O)N
InChI
1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKey
FFEARJCKVFRZRR-BYPYZUCNSA-N
CAS Number
CAS 63-68-3
ChEBI ID
CHEBI:16643
Herb ID
HBIN034827
SymMap ID
SMIT16474
TTD Drug ID
D0PO8E
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. A List of Drug(s) Whose Efficacy can be Enhanced by This NP
          Ciprofloxacin      Bacterial infection     Click to Show/Hide the Molecular Data of This Drug
                 Achieving Therapeutic Synergy     Click to Show/Hide
                    Representative Experiment Reporting the Effect of This Combination [2]
                    Detail(s)  Combination Info  click to show the detail info of this combination
                    In-vitro Model Pseudomonas aeruginosa strain PA01 Microorganism model Pseudomonas aeruginosa
                    In-vivo Model Mice with PA pneumonia were used as animal model in this study.
                    Experimental
                    Result(s)		 Intranasal L-Met treatment along with antibiotics can cure chronic PA lung infection in mice.
References
Reference 1 L-Methionine inhibits growth of human pancreatic cancer cells. Anticancer Drugs. 2014 Feb;25(2):200-3.
Reference 2 Chronic lung infection by Pseudomonas aeruginosa biofilm is cured by L-Methionine in combination with antibiotic therapy. Sci Rep. 2015 Nov 2;5:16043.
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