Natural Product (NP) Details
| General Information of the NP (ID: NP5738) | |||||
|---|---|---|---|---|---|
| Name |
Alpinia purpurata lectin
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| Species Origin | Alpinia purpurata ... | Click to Show/Hide | |||
| Alpinia purpurata | |||||
| Disease | Candidosis [ICD-11: 1F23] | Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. A List of Drug(s) Whose Resistance can be Reversed by This NP | ||||||
| Fluconazole | Fungal infection | Click to Show/Hide the Molecular Data of This Drug | ||||
| Reversing Drug Resistance | Click to Show/Hide | |||||
| Representative Experiment Reporting the Effect of This Combination | [1] | |||||
| Detail(s) |
Combination Info
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| In-vitro Model | Pseudomonas aeruginosa UFPEDA-416 | Microorganism model | Pseudomonas aeruginosa | |||
| Pseudomonas aeruginosa UFPEDA-02 | Microorganism model | Pseudomonas aeruginosa | ||||
| Experimental
Result(s) |
ApuL showed synergistic action in combination with antibiotics. | |||||
| β. A List of Drug(s) Whose Efficacy can be Enhanced by This NP | ||||||
| Oxacillin + Fluconazole | Click to Show/Hide the Molecular Data of This Drug | |||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Representative Experiment Reporting the Effect of This Combination | [1] | |||||
| Detail(s) |
Combination Info
click to show the detail info of this combination
|
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| In-vitro Model | Staphylococcus aureus | Microorganism model | Staphylococcus aureus | |||
| Pseudomonas aeruginosa | Microorganism model | Pseudomonas aeruginosa | ||||
| Experimental
Result(s) |
ApuL-oxacillin combination showed synergistic effect on the oxacillin-resistant isolates UFPEDA-670 and 671, which were not sensitive to lectin alone. | |||||
