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Drug Combination Details

General Information of the Combination (ID: C62269)
Name Alpinia purpurata lectin   NP Info  + Fluconazole   Drug Info 
Structure +
Disease
Staphylococcus infection [ICD-11: 1C41]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Reversing Drug Resistance by This Combination
                 Reversing Drug Resistance     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model Pseudomonas aeruginosa UFPEDA-416 Microorganism model Pseudomonas aeruginosa
Pseudomonas aeruginosa UFPEDA-02 Microorganism model Pseudomonas aeruginosa
                    Experimental
                    Result(s)
ApuL showed synergistic action in combination with antibiotics.
References
Reference 1 Antimicrobial potential of Alpinia purpurata lectin (ApuL): Growth inhibitory action, synergistic effects in combination with antibiotics, and antibiofilm activity. Microb Pathog. 2018 Nov;124:152-162.
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Cite NPCDR
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Correspondence

X. N. Sun, Y. T. Zhang, Y. Zhou, X. C. Lian, L. L. Yan, T. Pan, T. Jin, H. Xie, Z. M. Liang, W. Q. Qiu, J. X. Wang, Z. R. Li, F. Zhu*, X. B. Sui*. NPCDR: natural product-based drug combination and its disease-specific molecular regulation. Nucleic Acids Research. 50(D1): 1324-1333 (2020). PMID: 34664659

Prof. Feng ZHU  (zhufeng@zju.edu.cn)

College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China


Prof. Xinbing SUI  (hzzju@hznu.edu.cn)

School of Pharmacy and Department of Medical Oncology, the Affiliated Hospital of Hangzhou Normal University, Hangzhou Normal University, Hangzhou, China