Natural Product (NP) Details
| General Information of the NP (ID: NP6632) | |||||
|---|---|---|---|---|---|
| Name |
Panax ginseng total saponins
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| Species Origin | Panax ginseng ... | Click to Show/Hide | |||
| Panax ginseng | |||||
| Disease | Acute coronary syndrome [ICD-11: BA4Z] | Investigative | [1] | ||
| Herb ID | |||||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. A List of Drug(s) Whose Efficacy can be Enhanced by This NP | ||||||
| 5-fluorouracil | Solid tumour/cancer | Click to Show/Hide the Molecular Data of This Drug | ||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Representative Experiment Reporting the Effect of This Combination | [2] | |||||
| Detail(s) |
Combination Info
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| In-vivo Model | The mice were administered with AMO, PGS and AP respectively for 11 days, and intraperitoneally injected with 5-FU for 6 days since the 3rd day of the experiment. | |||||
| Experimental
Result(s) |
Combination of AMO and PGS, not AMO or PGS alone, significantly ameliorated diarrhea, inhibited intestinal pathology, and modulated gut microbial structure in 5-FU induced mice. | |||||
