Molecule Details

Natural Product(s) of This Target
1 Spiramycin  NP Info  Approved Streptomyces ambofaciens
Drug(s) of This Target
1 Chloramphenicol  Drug Info  Approved Bacterial infection
2 Linezolid  Drug Info  Approved Bacterial infection
References
Reference 1 The apicoplast as an antimalarial drug target. Drug Resist Updat. 2001 Jun;4(3):145-51.
Reference 2 Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin. Mol Microbiol. 2004 Dec;54(5):1287-94.
Reference 3 Genome sequencing of linezolid-resistant Streptococcus pneumoniae mutants reveals novel mechanisms of resistance. Genome Res. 2009 Jul;19(7):1214-23.