Molecule Details
| General Information of the Molecule | ||||
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| Name |
C-X-C motif chemokine 1 (CXCL1)
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| Synonyms |
SCYB1; Neutrophil-activating protein 3; NAP-3; Melanoma growth stimulatory activity; MGSA; Growth-regulated alpha protein; Growth regulated protein; GROA; GRO1; GRO-alpha(1-73); GRO-alpha; GRO-a protein; GRO
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| Gene Name |
CXCL1
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| Gene ID | ||||
| Sequence |
MARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSV
NVKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNSDKSN Click to Show/Hide
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| Function |
May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. Has chemotactic activity for neutrophils.
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| Uniprot ID | ||||
| Pfam | ||||
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| Natural Product(s) of This Target | ||||
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| 1 | Xanthohumol | NP Info | Investigative | Humulus lupulus |