Molecule Details
| General Information of the Molecule | ||||
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| Name |
Apoptosis regulator Bcl-W (BCL-W)
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| Synonyms |
KIAA0271; Bcl2-L-2; Bcl-2-like protein 2; BCLW
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| Gene Name |
BCL2L2
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| Gene ID | ||||
| Sequence |
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRT
FSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVG QVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVAL GALVTVGAFFASK Click to Show/Hide
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| Function |
Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX. Promotes cell survival.
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| Uniprot ID | ||||
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| Pfam | ||||
| KEGG ID | ||||
| TTD ID | ||||
| A List of Drug Combination(s) Able to Regulate This Molecule | ||||
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| Expression Regulation | Click to Show/Hide the Drug Combination Regulating This Molecule | |||
| Down-regulation | Click to Show/Hide | |||
| Drug Combination 1 Down-regulating the Expression of This Molecule | [1] | |||
| Detail(s) |
Combination Info
click to show the detail info of this combination
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| Name | Curcumin NP Info | + | Mitomycin C Drug Info | |
| Structure |
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| Drug(s) of This Target | ||||
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| 1 | ABT-263 | Drug Info | Phase 2 | Chronic lymphocytic leukaemia |