Molecule Details
| General Information of the Molecule | ||||
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| Name |
Bacterial DNA gyrase (Bact gyrase)
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| Synonyms |
DNA gyrase
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| Gene Name |
Bact gyrA; Bact gyrB
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| Function |
DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.
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| Uniprot ID | ||||
| TTD ID | ||||
| Drug(s) of This Target | ||||
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| 1 | Ciprofloxacin | Drug Info | Approved | Bacterial infection |
| 2 | Ofloxacin | Drug Info | Approved | Bacterial infection |
| References | ||||
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| Reference 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||