Drug Combination Details
| General Information of the Combination (ID: C17746) | |||||
|---|---|---|---|---|---|
| Name | Xylitol NP Info | + | Sucrose Drug Info | ||
| Structure |
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+ |
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| Disease |
Staphylococcus infection
[ICD-11: 1C41]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Obsborne-Mendel rats were inoculated once with a heavy suspension of S. mutans 50B4, serotype d, of human origin. | |||||
| Experimental
Result(s) |
This study confirms the suggested therapeutic effect of xylitol even when mixed with sucrose, while nonspecific effects were eliminated. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Anti-cariogenic and remineralizing properties of xylitol in combination with sucrose in rats inoculated with Streptococcus mutans. Caries Res. 1984;18(3):269-77. | |||
