Drug Combination Details
| General Information of the Combination (ID: C28407) | |||||
|---|---|---|---|---|---|
| Name | Magnolol NP Info | + | Oxaliplatin Drug Info | ||
| Structure |
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+ |
|
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| Disease |
Gastrointestinal stromal tumor
[ICD-11: 2B5B]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Decreasing Adverse Drug Reaction by This Combination | ||||||
| Decreasing Adverse Drug Reaction | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | p105 | Molecule Info |
Pathway MAP
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| Experimental
Result(s) |
MG could prevent the development and progression of mucositis induced by oxaliplatin through multipathway. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Protective effect of magnolol on oxaliplatin-induced intestinal injury in mice. Phytother Res. 2019 Apr;33(4):1161-1172. | |||
