Drug Combination Details
| General Information of the Combination (ID: C33551) | |||||
|---|---|---|---|---|---|
| Name | d-tubocurarine NP Info | + | Vecuronium Drug Info | ||
| Structure |
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+ |
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| Disease |
Neuromuscular blockage
[ICD-11: NE60]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vivo Model | Clinical trial | |||||
| Experimental
Result(s) |
Combination of vecuronium plus d-tubocurarine to be significantly more potent than would be expected from a simple additive effect of the individual drugs given alone. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Vecuronium and d-tubocurarine combination: potentiation of effect. Anesth Analg. 1985 Jul;64(7):711-4. | |||
