Drug Combination Details

General Information of the Combination (ID: C47170)
Name Luteolin   NP Info  + Imatinib   Drug Info 
Structure +
Disease
Chronic myelogenous leukaemia [ICD-11: 2A20]
Investigative [1]
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally
    α. Enhancing Drug Efficacy by This Combination
                 Augmenting Drug Sensitivity     Click to Show/Hide
                    Experiment 1 Reporting the Effect of This Combination [1]
                    In-vitro Model K-562 CVCL_0004 Chronic myelogenous leukemia Homo sapiens
                    Experimental
                    Result(s)		 Combination treatment may provide better outcomes in terms of cytotoxicity and thus reduce the dosages of imatinib used.
References
Reference 1 Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method. Balkan Med J. 2019 Feb 28;36(2):96-105.
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