Drug Combination Details
| General Information of the Combination (ID: C53641) | |||||
|---|---|---|---|---|---|
| Name | Antineoplaston A10 NP Info | + | Cis-diamminedichloroplatinum Drug Info | ||
| Structure |
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+ |
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| Disease |
Hepatocellular carcinoma
[ICD-11: 2C12]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | KIM-1 | CVCL_7969 | Adult hepatocellular carcinoma | Homo sapiens | ||
| In-vivo Model | The KIM-1 cell suspension was implanted subcutaneously in BALB/c athymic mice. | |||||
| Experimental
Result(s) |
The inhibitory effect of the combination of antineoplaston A-10 injection with a small dose of cis-diamminedichloroplatinum on cell and tumor growth of human hepatocellular carcinoma. | |||||