Drug Combination Details
| General Information of the Combination (ID: C62804) | |||||
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| Name | Cladribine | + | Gemcitabine + Busulfan + Vorinostat | ||
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| Name | Cladribine NP Info | Drug Info | |||
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| Disease |
Acute lymphoblastic leukemia
[ICD-11: 2B33]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| In-vitro Model | J45.01 | CVCL_2530 | T acute lymphoblastic leukemia | Homo sapiens | ||
| U-937 | CVCL_0007 | Adult acute monocytic leukemia | Homo sapiens | |||
| Experimental
Result(s) |
The Clad+Gem+Bu+SAHA combination provides synergistic cytotoxicity in lymphoma cell lines. | |||||
