Drug Combination Details
| General Information of the Combination (ID: C68939) | |||||
|---|---|---|---|---|---|
| Name | Geraniol NP Info | + | Simvastatin Drug Info | ||
| Structure |
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+ |
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| Disease |
Hepatocellular carcinoma
[ICD-11: 2C12]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Biological
Regulation |
Inhibition | Cholesterol biosynthesis | ||||
| In-vitro Model | Hep-G2 | CVCL_0027 | Hepatocellular carcinoma | Homo sapiens | ||
| Experimental
Result(s) |
Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line. Cell Biochem Funct. 2011 Aug;29(6):452-8. | |||
