Drug Combination Details
| General Information of the Combination (ID: C79823) | |||||
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| Name | Green tea catechins | + | Metronidazole + Tetracycline | ||
| Click to Show/Hide the Each NP or Drug Information of This Combination | |||||
| Name | Green tea catechins NP Info | Drug Info | |||
| Structure |
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| Name | Drug Info | ||||
| Structure |
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| Disease |
Periodontal disease
[ICD-11: DA0C]
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Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Up-regulation | Expression | HTRA1 | Molecule Info | ||
| In-vitro Model | Porphyromonas gingivalis | Microorganism model | Porphyromonas gingivalis | |||
| Experimental
Result(s) |
Green tea catechins potentiate the effect of antibiotics and modulate adherence and gene expression in Porphyromonas gingivalis. | |||||
| References | ||||
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| Reference 1 | Green tea catechins potentiate the effect of antibiotics and modulate adherence and gene expression in Porphyromonas gingivalis. Arch Oral Biol. 2016 May;65:35-43. | |||
