Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally |
α. Enhancing Drug Efficacy by This Combination |
Achieving Therapeutic Synergy |
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Experiment 1 Reporting the Effect of This Combination |
[1] |
In-vitro Model |
Chinese hamster ovary cell line |
Healthy |
Cricetulus griseus |
In-vivo Model |
The animal models were established in Sprague Dawley rats by continuous infusion of aconitine into the caudal vein or vena jugularis externa. |
Experimental
Result(s) |
The anti-arrhythmic effect of the combination of TTX and LID was greater than that of either TTX or LID alone. |