Drug Details
| General Information of the Drug (ID: DR7648) | ||||
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| Name |
Sodium ferulate
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| Synonyms |
Sodium ferulate; 24276-84-4; Sodium ferulic; Sodium 3-(4-hydroxy-3-methoxyphenyl)acrylate; Ferulic acid (sodium); ferulic acid sodium salt; UNII-OIS7F1IRQK; OIS7F1IRQK; Sodium 3-methoxy-4-hydroxycinnamate; Monosodium 4-hydroxy-3-methoxycinnamate; Monosodium 3-(4-hydroxy-3-methoxyphenyl)-2-propenoate; 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid monosodium salt; sodium (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate; sodium;(E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; ferulic acid sodium; MFCD00075727; Ferulicacidsodiumsalt; C10H9O4.Na; Cinnamic acid, 4-hydroxy-3-methoxy-, monosodium salt; CHEMBL4594451; FEMA NO. 3812; HY-N0060A; DTXSID80894080; CHEBI:114954; BCP05695; s4740; AKOS015890674; AC-7966; ACN-035276; CCG-266691; CS-5275; AS-12205; K-6527; Q3092716; W-200547; sodium (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; sodium (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate; 151109-65-8
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| Molecular Type |
Small molecule
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| Disease | Influenza [ICD-11: 1E30] | Investigative | [1] | |
| Structure |
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| Click to Show/Hide the Molecular Information and External Link(s) of This Natural Product | ||||
| Formula |
C10H9NaO4
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| PubChem CID | ||||
| Canonical SMILES |
COC1=C(C=CC(=C1)C=CC(=O)[O-])O.[Na+]
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| InChI |
1S/C10H10O4.Na/c1-14-9-6-7(2-4-8(9)11)3-5-10(12)13;/h2-6,11H,1H3,(H,12,13);/q;+1/p-1/b5-3+;
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| InChIKey |
NCTHNHPAQAVBEB-WGCWOXMQSA-M
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| CAS Number |
CAS 24276-84-4
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| ChEBI ID | ||||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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| α. A List of Natural Product(s) Able to Enhance the Efficacy of This Drug | ||||||
| Oxymatrine | Sophora flavescens | Click to Show/Hide the Molecular Data of This NP | ||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Representative Experiment Reporting the Effect of This Combination | [2] | |||||
| Detail(s) |
Combination Info
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| Molecule(s)
Regulation |
Down-regulation | Expression | IL19 | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | p105 | Molecule Info |
Pathway MAP
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| In-vivo Model | Swiss mice (18-20 g) and Sprague-Dawley rats (120-150 g) were used in this study. | |||||
| Experimental
Result(s) |
SF and OMT combination had an obvious protective effect on PQ-induced lung injury. The anti-infammatory and antioxidant effect might be involved in the mechanism. | |||||
