Drug Combination Details
| General Information of the Combination (ID: C92831) | |||||
|---|---|---|---|---|---|
| Name | Sulforaphane NP Info | + | Fernblock Drug Info | ||
| Structure |
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+ |
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| Disease |
Melanoma
[ICD-11: 2C30]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Enhancing Drug Efficacy by This Combination | ||||||
| Achieving Therapeutic Synergy | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | IL1B | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | MMP-1 | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | MMP-3 | Molecule Info |
Pathway MAP
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| In-vitro Model | WM115 | CVCL_0040 | Melanoma | Homo sapiens | ||
| WM266-4 | CVCL_2765 | Melanoma | Homo sapiens | |||
| Experimental
Result(s) |
The combination of sulforaphane and fernblock XP improves individual beneficial effects in normal and neoplastic human skin cell lines. | |||||
| References | ||||
|---|---|---|---|---|
| Reference 1 | The Combination of Sulforaphane and Fernblock ? XP Improves Individual Beneficial Effects in Normal and Neoplastic Human Skin Cell Lines. Nutrients. 2020 May 30;12(6):1608. | |||
