Drug Details
General Information of the Drug (ID: DR5752) | ||||
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Name |
Androgen
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Synonyms |
testosterone propionate; 57-85-2; Agovirin; Androlon; Androteston; Aquaviron; Hormoteston; Enarmon; Bio-testiculina; Androtest P; Androsteston; Sterandryl; Testonique; Andronate; Masenate; Orchiol; Orchistin; Pantestin; Propiokan; Solvotest; Synandrol; Synerone; Telipex; Testaform; Testodet; Testodrin; Testogen; Testolets; Testormol; Testosid; Testoxyl; Testrex; Tostrin; Uniteston; Nasdol; Vulvan; Enarmon-oil; Neo-Hombreol; Okasa-Mascul; Andrusol-P; Oreton propionate; Recthormone testosterone; NSC 9166; Testosteron propionate; 17beta-(Propionyloxy)androst-4-en-3-one; Testosterone-17-propionate; Homandren (amps); Androgen; UNII-WI93Z9138A; CHEMBL1170; CHEBI:9466; (17beta)-3-oxoandrost-4-en-17-yl propanoate; (17beta)-3-oxoandrost-4-en-17-yl propionate; Testosterone-17.beta.-propionate; WI93Z9138A; NSC-9166; Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17b)-; [(8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl] propanoate; NCGC00016254-01; 17-propionyl-17beta-hydroxyandrost-4-en-3-one; DSSTox_CID_16515; DSSTox_RID_79286; DSSTox_GSID_36515; Orchisterone; Testosteroni propionas; CAS-57-85-2; CCRIS 575; Testoviron (ampule); testosteron-17-propionat; Testosterone-17beta propionate; Testosterone-17beta-propionate; Testosterone-17-beta-propionate; EINECS 200-351-1; Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17.beta.)-; AI3-26378; 17beta-Hydroxyandrost-4-en-3-one propionate; 17beta-Hydroxy-4-androsten-3-one 17-propionate; Testosterone propionate [USP:JAN]; Androst-4-en-3-one, 17beta-hydroxy-, propionate; delta(sup 4)-Androstene-17-beta-propionate-3-one; Prestwick_432; 17beta-Hydroxyandrost-4-en-3-one-17beta-propionate; Testex (TN); 17.beta.-(Propionyloxy)androst-4-en-3-one; Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17beta)-; .DELTA.4-androstene-17.beta.-propionate-3-one; 17.beta.-hydroxyandrost-4-en-3-one, propionate; 3-Oxoandrost-4-en-17-yl propionate, (17.beta.)-; Prestwick0_000401; Prestwick1_000401; Prestwick2_000401; Prestwick3_000401; Androst-4-en-3-one, 17.beta.-hydroxy-, propionate; 17-(1-Oxopropoxy)androst-4-en-3-one, (17.beta.)-; Testosterone propionate ciii; SCHEMBL4044; BSPBio_000322; MLS002153796; Testosterone propionate, solid; SPBio_002261; BPBio1_000356; GTPL7100; Testosterone-17.beta.propionate; DTXSID9036515; Testosterone propionate [Androgenic (anabolic) steroids]; NSC9166; HMS1569A04; HMS2096A04; HMS2272K06; HMS3713A04; Testosterone propionate (Agovirin); ZINC490791; HY-B1269; Tox21_110330; Tox21_302270; BBL029912; BDBM50215709; LMST02020076; MFCD00003653; NRB-03689; STK801834; Testosterone propionate (JP17/USP); AKOS005622513; AKOS015842719; Tox21_110330_1; CCG-220401; CS-4905; DB01420; MCULE-8627319345; NCGC00179602-01; NCGC00179602-03; NCGC00179602-06; NCGC00255481-01; AC-12172; AC-33160; SMR000058348; VS-09499; BCP0726000215; C08158; D00959; 003T653; Testosterone Propionate 1.0 mg/ml in Acetonitrile; Testosterone propionate, tested according to Ph.Eur.; W-105436; BRD-K90553655-001-03-6; Q10354588; WLN: L E5 B666 OV MUTJ A E FO52 -B&AEF; Androst-4-en-3-one, 17-(1-oxopropoxy)-(17.beta.)-; Testosterone propionate, British Pharmacopoeia (BP) Reference Standard; Testosterone propionate, European Pharmacopoeia (EP) Reference Standard; Testosterone propionate, United States Pharmacopeia (USP) Reference Standard; (1S,3aS,3bR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl propanoate; Propionic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester; Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester; Propionic acid 10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester(Testosterone Propionate); Testosterone propionate for system suitability, European Pharmacopoeia (EP) Reference Standard
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Molecular Type |
Small molecule
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Disease | Diminished ovarian reserve [ICD-11: 5A80] | Investigative | [1] | |
Structure |
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Click to Show/Hide the Molecular Information and External Link(s) of This Natural Product | ||||
Formula |
C22H32O3
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PubChem CID | ||||
Canonical SMILES |
CCC(=O)OC1CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C
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InChI |
1S/C22H32O3/c1-4-20(24)25-19-8-7-17-16-6-5-14-13-15(23)9-11-21(14,2)18(16)10-12-22(17,19)3/h13,16-19H,4-12H2,1-3H3/t16-,17-,18-,19-,21-,22-/m0/s1
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InChIKey |
PDMMFKSKQVNJMI-BLQWBTBKSA-N
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CAS Number |
CAS 57-85-2
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ChEBI ID | ||||
TTD Drug ID |
Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
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α. A List of Natural Product(s) Able to Enhance the Efficacy of This Drug | ||||||
Arsenic trioxide | Realgar and orpiment | Click to Show/Hide the Molecular Data of This NP | ||||
Achieving Therapeutic Synergy | Click to Show/Hide | |||||
Representative Experiment Reporting the Effect of This Combination | [2] | |||||
Detail(s) | Combination Info click to show the detail info of this combination | |||||
Molecule(s)
Regulation |
Down-regulation | Phosphorylation | AKT1 | Molecule Info |
Pathway MAP
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Up-regulation | Expression | ATG5 | Molecule Info |
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Down-regulation | Expression | BCL-2 | Molecule Info |
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Up-regulation | Cleavage | CASP3 | Molecule Info |
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Down-regulation | Phosphorylation | CYB5R2 | Molecule Info |
Pathway MAP
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Up-regulation | Expression | MAP1LC3A | Molecule Info |
Pathway MAP
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Down-regulation | Phosphorylation | mTOR | Molecule Info |
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Up-regulation | Cleavage | PARP1 | Molecule Info |
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Down-regulation | Phosphorylation | S6K1 | Molecule Info |
Pathway MAP
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Up-regulation | Expression | SQSTM1 | Molecule Info |
Pathway MAP
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In-vitro Model | LNCaP | CVCL_0395 | Prostate carcinoma | Homo sapiens | ||
PC-3 | CVCL_0035 | Prostate carcinoma | Homo sapiens | |||
Experimental
Result(s) |
Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cells. |