Drug Combination Details
| General Information of the Combination (ID: C84931) | |||||
|---|---|---|---|---|---|
| Name | Acteoside NP Info | + | Dextran sulfate sodium Drug Info | ||
| Structure |
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+ |
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| Disease |
Colitis
[ICD-11: 1A40]
|
Investigative | [1] | ||
| Combinatorial Therapeutic Effect(s) Validated Clinically or Experimentally | ||||||
|---|---|---|---|---|---|---|
| α. Decreasing Adverse Drug Reaction by This Combination | ||||||
| Decreasing Adverse Drug Reaction | Click to Show/Hide | |||||
| Experiment 1 Reporting the Effect of This Combination | [1] | |||||
| Molecule(s)
Regulation |
Down-regulation | Expression | CSF2 | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | IFNG | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | IL10 | Molecule Info |
Pathway MAP
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| Down-regulation | Expression | TNF | Molecule Info |
Pathway MAP
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| In-vivo Model | Female Balb/c mice weighing 20-22 g were used in this study. | |||||
| Experimental
Result(s) |
In vivo treatment with the herbal phenylethanoid acteoside ameliorates intestinal inflammation in dextran sulphate sodium-induced colitis. | |||||
